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Run Data Run

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Building in public. AI experiments, lessons learned, and the journey of treating AI as a multiplier.

Earlier posts (13 more)
Last 30 Days: The AI Scientists
Jul 12, 2026

Last 30 Days: The AI Scientists

Four autonomous discovery systems cleared peer review in four months. Every one of them was already a year old. Here is the full sweep, including the reliability research nobody is reading.

The Year Nature Caught Up
Jul 12, 2026

The Year Nature Caught Up

Robin found a new use for an old glaucoma drug and landed in Nature. The preprint was fourteen months old. Once you notice that lag, you notice it everywhere.

How I Actually Stay Current on AI (I Built a Wire)
Jul 9, 2026

How I Actually Stay Current on AI (I Built a Wire)

The question I get asked most, and the system that answers it.

AI Ate the Keyboard. Now It Has to Eat the Queue.
Jul 7, 2026

AI Ate the Keyboard. Now It Has to Eat the Queue.

Software stopped being the limiting factor. Process didn't. In biopharma and any patient-facing industry, the queue is the patient.

Every AI Book Tells You What to Think. This One Is About What Your Hands Do.
Jul 6, 2026

Every AI Book Tells You What to Think. This One Is About What Your Hands Do.

There is a whole shelf of AI books for leaders now. I read enough of them to know why I wrote a different kind.

The Gap, and the Book That Came Out of It
Jul 1, 2026

The Gap, and the Book That Came Out of It

There's a line splitting the AI conversation that nobody's arguing about, because most people don't know it's there. I've spent months on the wrong-versus-right side of it. The book is out now.

Claude Science and the boring 80 percent
Jun 30, 2026

Claude Science and the boring 80 percent

Anthropic shipped a workbench, not a miracle. The model is the commodity layer. The harness around it is the moat.

Borrowed Iron
Jun 28, 2026

Borrowed Iron

A borrowed eight-GPU node, a global-health mission, and a crew of six: me, a founder, and four interns.

The Harness Is the Moat
Jun 25, 2026

The Harness Is the Moat

The model is the part of your AI strategy you can order off a price sheet. The thing you build around it is the part nobody can copy. I made mine public so you can see the shape of it.

Jun 23, 2026

Ep. 1: Two Groups

Same AI, same task, a different result. The difference isn't the model.

What AI Didn't Reprice
Jun 22, 2026

What AI Didn't Reprice

AI marked down almost every skill on your team this year. One it marked up. If you run a budget, that one number should change where you're spending.

You Don't Have to Write the Code
Jun 17, 2026

You Don't Have to Write the Code

Anthropic watched 400,000 sessions with a coding agent and found that what predicts success isn't your job or your syntax. It's whether you understand the work. That changes who gets to build, and...

The Wrong Tool Problem in Genomic AI
Jun 14, 2026

The Wrong Tool Problem in Genomic AI

A leaderboard tells you which model wins. It can't tell you that you picked the wrong kind of model.

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